Nevertheless, the acute toxicity of buprofezin in aquatic organisms is lacking. The toxicological effects of pesticide pollution on non target aquatic organisms in the environment can be examined by detecting changes in organisms at the developmental, physiological, biochemical or molecular levels, which can provide biomarker tools in monitoring 
environment quality. The developing fish AbMole Taltirelin embryo or larvae is generally considered to be the most sensitive stage in the life cycle of a teleost fish being particularly sensitive to low level of environmental pollutants. These biomarkers can measure the AbMole Terbuthylazine interaction between environmental xenobiotics and biological effects. Inhibition and induction of these biomarkers are a good approach to measure potential impacts of pollutants on aquatic organisms. Most of the catfish farms in Malaysia are located in and around the agriculture fields or their source of water is continuously in contact with the paddy ecosystem in which lot of pesticides, weedicides and insecticides are routinely used. African catfish is a high fecund fish species, can be easily bred and maintained in laboratory. The candidate fish is very popular and farmed fish species in Malaysia and commonly found in paddy fields. To the best of our knowledge there is no earlier studies so far have been conducted to understand the toxic potential of buprofezin in fishes commonly found in paddy ecosystem. Keeping in view of these aspects, a study was conducted to evaluate the potential effects of buprofezin on the embryo and larvae of African catfish, Clarias gariepinus. The data reported in this study would be useful for the management of paddy ecosystem with respect to the regulation of buprofezin usage in rice fields. It has been noticed that increasing buprofezin concentrations had significant effects on hatching success and survival of African catfish embryos and larvae. Takimoto et al. also reported that timing of exposure of O. latipes embryos to sub lethal concentrations of the organophosphate fenitrothion resulted in significantly different degrees of mortality and hatching success. The present results strongly support the earlier findings by Marty et al., Takimoto et al. and Ayd?n and Koprucu. Developmental abnormalities, such as irregular head shape, lordosis, yolk sac edema, body arcuation, tissue ulceration, pericardial edema and pericardial hemorrhage were also found in the group exposed to buprofezin. To our knowledge, the present study is one of the first to evaluate developmental toxicity in fish caused by exposure to buprofezin in aquatic environments. These studies demonstrate that organisms in the early stages of embryonic development are usually more sensitive to toxicological effects.